High channel count electrophysiology, hardware data analysis and scaling - Timothy Harris
Speaker
Timothy Harris
Thursday, October 3, 2019
Wu Tsai Neurosciences Institute
Clark Center Auditorium
Wu Tsai Neurosciences Institute Seminar Series Presents
Timothy Harris, PhD
Janelia Senior Fellow,
Janelia Research Campus - HHMI
Host: Nick Melosh
Abstract
Recent technologies have increased routine extracellular recording capacity from dozens to thousands of neurons. A next generation of hardware projects 10’s to 100’s of thousand neurons. I will review our work to develop high channel count devices, Neuropixels, and the prospects for another 10-50X capacity increase. This data volume has created bottlenecks for analysis, frequently aspiring to produce single neuron activity records, called spike sorting. I will compare different algorithms, show their frequent alarmingly divergent results, and discuss what fraction of this new data volume seems reliable. Finally, I will open a discussion of limits, how much is enough?
Contact Email
neuroscience [at] stanford.edu
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